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Manuscript deadline
31 October 2020

Cover image - Journal of Immunoassay and Immunochemistry

Journal of Immunoassay and Immunochemistry

Special Issue Editor(s)

Prof. Dr. Cristiana Tanase, "Victor Babes" National Institute of Pathology, Bucharest, Romania
[email protected]

Prof. Dr. Habil. Monica Neagu, "Victor Babes" National Institute of Pathology, Bucharest, Romania
[email protected]

Dr. Radu Albulescu, National Institute for Chemical-Pharmaceutical R&D, Bucharest, Romania

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Understanding COVID-19 immunity – reality and challenges

As we are facing one of the major outbreaks of viral infection of the modern history, the SARS-Cov2 pandemic, all the aspects of immune response to viral infection are explored in an accelerated pace. Thus, passive immunization that covers the administration of already mature antibodies (immunoglobulins) was one of the first attempts to rapidly overcome the viral infectious disease. Artificially induced passive immunity is sustained by transferring antibodies by systemic, intravenous, or oral routes. Passive immunity is limited in time thus, to sustain this immunity, preformed antibodies should be re-introduced. Another type of immunization is the active one where the specific immune response is induced by vaccination. Vaccine development workflow in this type of viral infection has witnessed one of the high speeds in the modern era. There are at least 145 types of vaccines that are in several development phases and probably many more will be initiated in the following months. The main issue in the vaccination domain is the time span of the immune memory. Hence, the titer of specific anti-viral antibodies and the maintenance of these titers must be solved by vaccination. The immune cells that are endowed with memory, B and T lymphocytes would sustain the immunological memory. In all these aspects, the current viral pandemic, novel approaches are to be designed and tested.

We invite authors to tackle within their paper all these aspects, but not restricted to:

  • Acquired and innate immunity in SARS-Cov2 infection
  • Herd immunity in acute viral respiratory infection
  • Inter-relation of immunity and coronavirus infection in various pathologies like cancers, diabetes, cardiovascular disease, neurological disease, skin diseases and so on
  • Main technologies for SARS-Cov2 detection
  • Vaccination in coronaviridae infections
  • Therapeutic approaches enhancing immunity in COVID-19

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