Organogenesis, the process by which organs and tissues are formed during embryonic development, is a fascinating and complex field of study. Biomedical engineering has the potential to revolutionize our understanding of organogenesis and enable the development of cutting-edge therapies and interventions for a wide range of diseases and conditions. This special issue of Organogenesis will focus on the latest medical applications of biomedical engineering, highlighting innovative research and advancements at the intersection of these two fields.
The aim of this special issue is to showcase the most recent breakthroughs in biomedical engineering related to organogenesis, with a focus on the development of novel medical applications, treatments, and therapies. By providing a platform for researchers to share their work, we hope to foster interdisciplinary collaboration and stimulate further advancements in this rapidly evolving field.
Topics of interest include, but are not limited to:
- Biofabrication of organs and tissues for medical applications: a. 3D bioprinting of functional tissues and organs for transplantation b. Scaffold-based and scaffold-free approaches to tissue engineering for regenerative medicine c. Biomaterials and hydrogels for organ and tissue engineering in clinical settings
- Biomimetic models for medical applications: a. Organ-on-a-chip technologies for drug discovery and personalized medicine b. Microfluidic systems for disease modeling and therapeutic development c. In vitro models of organ development, regeneration, and disease
- Stem cell engineering and regenerative medicine: a. Induced pluripotent stem cells (iPSCs) and organoids for tissue regeneration and disease modeling b. Engineering cellular microenvironments for directed differentiation and clinical applications c. Cell reprogramming for organ regeneration and personalized medicine
- Advanced imaging and analysis techniques for medical applications: a. High-resolution imaging and computational modeling of organ development for diagnostic and therapeutic purposes b. Machine learning and artificial intelligence in medical organogenesis research c. Quantitative approaches for studying organ morphogenesis, function, and treatment response
- Biomedical engineering for organ transplantation and therapy: a. Bioengineered organs and tissues for transplantation and regenerative medicine b. Immunomodulatory strategies for engineered tissues in clinical settings c. Targeted drug delivery and gene editing for organogenesis-related diseases and disorders
- Integrate mechanistic experiments that use synthetic biology tools, genetic engineering, protein modulation, cellular engineering, and tissue generation will also be considered.
