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Submit a Manuscript to the Journal
International Journal of Hyperthermia

For a Special Issue on
Computational modeling in hyperthermia

Manuscript deadline
01 April 2022

Cover image - International Journal of Hyperthermia

Special Issue Editor(s)

Margarethus M. (Maarten) Paulides, Eindhoven University of Technology
[email protected]

Hana Dobsicek Trefna, Chalmers University of Technology
[email protected]

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Computational modeling in hyperthermia

The success of cancer hyperthermia (HT) treatments is strongly dependent on the temperatures achieved in the tumor and healthy tissues as it correlates with treatment efficacy and safety, respectively. Computational modelling based hyperthermia treatment planning (HTP) have become pivotal for treatment optimization due to the possibility for pre-treatment planning, optimization and decision making, as well as real-time treatment guidance. The same computational methods deployed in HTP are also used for in silico studies. These models are of great relevance for the development of new HT devices and treatment approaches. Hence computational modelling has an established but still expanding role in hyperthermia.

To support progress by computational modelling studies, 3D patient models have been recently developed and made available for the HT community (Erasmus MC Virtual Patient Repository - EVPR). In addition, a comprehensive set of applicator benchmarks, efficacy and safety optimization algorithms, simulation settings and clinical parameters, were developed to establish benchmarks for method comparison and code verification in the context of the ongoing 2021 ESHO Grand Challenge (https://www.esho.info/). The 2021 ESHO Grand Challenge aims at establishing guidelines to promote standardization within the hyperthermia community such that novel approaches can quickly prove their benefit as quickly as possible in clinically relevant simulation scenarios in radiofrequency, microwave and ultrasound mediated hyperthermia.

The aim of this special issue is to display the full extends of computational modelling in hyperthermia by reviews and original papers. Hence, the special issue is focused at:

  1. Reviews that summarize progress on specific topics of computational modelling in hyperthermia when applied in pre-treatment planning, patient selection, real-time treatment guidance, applicator optimization, etc.
  2. Original papers demonstrating the benefit of computational modelling in hyperthermia. Specifically, papers are sought that exploit the benchmarks defined in the 2021 ESHO Grand Challenge to standardize the assessments. These papers will also participate in the challenge.

Submission Instructions

When uploading your paper, please make sure to select the special issue "computational modelling in hyperthermia". Note that both reviews and original contributions on investigation or application of computational modelling in hyperthermia are included. The deadline for submission is April 1st, and publication is expected end of 2022.

Instructions for AuthorsSubmit an Article