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An Open Access Journal from Taylor & Francis

Now ranked in the Top 10 for Infectious Disease

2019 Impact Factor 5.542

Virulence is one of the top journals globally with a unique focus on pathogenicity and pathogenesis.

Virulence is the first international peer-reviewed journal of its kind with a specific focus on microbial pathogenicity, the infection process and host-pathogen interactions, including the interaction between host and environment.

To address the new infectious challenges, emerging infectious agents and antimicrobial resistance, there is a clear need for interdisciplinary research. As a multidisciplinary journal, Virulence brings together scientists and clinical researchers working on the 'pathogen,' the 'host' or the 'antimicrobial agents.' It is particularly interested in infection models and actual infections, in the mechanisms, severity and attenuation of infection. As a fully open access journal all articles are available for anyone to read anywhere, at any time, immediately on publication.

Virulence regularly publishes Special Issues on a range of topics. Explore Special Issues.

Malaria Special Issue

Read the latest Special Issue on Malaria.

Virulence is particularly interested in receiving manuscripts on:

  • Microbial pathogenicity–viruses (including HIV), bacteria, fungi, and parasites
  • Molecular and biological function of established and novel virulence factors
  • Identification, development and study of antimicrobial agents
  • Host-pathogen and pathogen-pathogen interactions
  • Host response to infection and immune responses to inhibitors, toxins, and other virulence factors
  • Mammalian, other vertebrate as well as invertebrate model organisms and hosts
  • Clinical trials evaluating all aspects of the infection process
  • Microbiome
  • Research on bio-terrorism agents
  • Vaccine development and evaluation
  • Diagnosis of infectious diseases
  • Infections in resource-limited settings


Virulence welcomes submission of original manuscripts pertaining to infection biology and disease in two flexible formats, either as research papers or reviews.

Click to find out more.


Meet our newest Editor-in-Chief

Kevin Tyler

Follow Kevin on Twitter @KevinMTyler

Kevin Tyler runs a cosmopolitan, multidisciplinary group taking a genomics led approach to tackling problems associated with a variety of (water borne and vector borne) microbial diseases supported by grants from the Wellcome Trust, the European Commission (Framework VI, VII, Horizon 2020 and Interreg) and the British Council for networks of research and collaboration across Europe, South America and Africa. He has served as an NTD expert to the European Commission and is an advocate for solutions to these diseases through his current role as the general secretary of the British Society for Parasitology.

His interest is focused at achieving an understanding of pathogen virulence - how and why new virulent lineages emerge and why some are profoundly affected by an infection which can be asymptomatic in others. His approach has been to utilize discoveries of specific pathogen biology and genetics from his laboratory to inform innovation and validation of novel diagnostics and therapeutics and public health approaches to tackling the diseases.

He has also been a proponent and pioneer of Open Access Publication and is a modernizer of effective communication and publication for research in communicable disease to enable access of the key scientific literature by scientists and clinicians in the more impoverished countries most affected by infectious disease. At the turn of the millennium he organized a series of internet conferences where scientists world-wide shared their work live, online and for free, guest Editing those articles for (perhaps) the first ever “open access” special issue of a traditional publication. He was Founder Editor of one of the first open access journals in infectious disease – (Kinetoplastid Biology and Disease), and was subsequently founder and Editor of the premier parasitology journal Parasites and Vectors and its popular Bugbitten community blog. As Editor-in-Chief of Virulence he aims to work with the global community of infectious disease biologists and clinicians, capitalizing on the newly gained open access format of virulence to democratise access, reduce barriers to readership and publication and increase the translational impact of the work published.

We recently conducted an interview with Kevin on Twitter to ask his views on the challenges facing the research community and the benefits of publishing open access.

Read the full Q&A

Article picks from recent Special Issues are highlighted below.

Endemic Mycoses


Cryptococcus neoformans yeast cells visualized by India Ink under phase contrast microscopy
Article Author
Sensing the heat and the host: Virulence determinants of Histoplasma capsulatum Sinem Beyhan & Anita Sil
Coccidioides immitis and posadasii; A review of their biology, genomics, pathogenesis, and host immunity Theo N. Kirkland & Joshua Fierer
Turning on virulence: Mechanisms that underpin the morphologic transition and pathogenicity of Blastomyces Joseph A. McBride MD, Gregory M. Gauthier MD & Bruce S. Klein MD
Regulatory T cells in paracoccidioidomycosis Vera L. G. Calich, Ronei L. Mamoni & Flávio V. Loures
The capsule of Cryptococcus neoformans Arturo Casadevall, Carolina Coelho, Radames J. B. Cordero et al.

Explore the latest research

Read the latest Coronavirus research published in the journal.
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Submit your research

Virulence is welcoming submissions. Find out how to submit.