OncoTargets and Therapy

Dove Medical Press is pleased to invite you to submit your research to the upcoming Article Collection “Cancer Immunotherapy: Harnessing the Immune System for Cancer Treatments” organized by Guest Advisor Dr. Anna Maria Di Giacomo in OncoTargets and Therapy.

In the last decade, harnessing the immune system with immune checkpoint blockades has achieved remarkable results in solid tumors of different histotypes, enabling durable responses and long-term survival. Despite these unprecedented results, primary or acquired resistance can limit its efficacy; therefore a deeper understanding of the underlying mechanism of resistance is crucial for the identification of novel therapeutic strategies in several clinical settings (e.g. adjuvant, neo-adjuvant setting, rare tumors, etc.). In this exciting scenario, to untangle the threads of immunotherapy, research needs to answer some key questions, ranging from the mechanistic exploration causing lack of response, to the identification of biomarkers, but also the development of novel immunotherapeutic modalities and their clinical applications.

In this regard, we are seeking original research, and review article submissions on the following topics:
• Immune-checkpoint blockade for cancer treatment: from biology to clinical results
• Therapeutic combinations of immune-modulating antibodies
• Immunotherapies for brain metastases and brain primary tumors
• Immunotherapies for ocular melanoma
• Immunotherapies for rare tumors
• Immunotherapy in adjuvant and neoadjuvant settings
• Mechanisms of immune escape and potential strategies to overcome resistance
• Epigenetic immune remodeling to improve the efficacy of cancer immunotherapies
• Harnessing T-cell metabolism to improve anti-tumor responses
• Microbioma and immune-checkpoint blockade therapy
• Beyond immune-checkpoint(s): new targets for cancer immunotherapy
• Imaging challenges of immunotherapy
• Biomarkers of immune response and toxicity in immunotherapy
• Radiomics and deep learning approach in cancer immunotherapy

 

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All manuscripts submitted to this Article Collection will undergo desk assessment and peer-review as part of our standard editorial process. Please review the journal Aims and Scope and author submission instructions prior to submitting a manuscript.

The deadline for submissions is 30th April 2024.

Please submit   your manuscript on our website, quoting the promo code ZDDYW to indicate that your submission is for consideration in this Article Collection.

Please contact Marya Baig at [email protected] with any queries and discount codes regarding this Article Collection.

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Article Collection Guest Advisor

Anna Maria Di Giacomo is an Associate Professor of Oncology at the University of Siena, Chair of the Early Phase Clinical Trial Center and Associate Director for the Center for Immuno-Oncology, Department of Oncology at the University Hospital of Siena. She is a member of the Associazione Italiana di Oncologia Medica (AIOM), the Italian Network for Tumour Biotherapy (NIBIT) Foundation, The Italian Melanoma Intergroup (IMI) and ESMO (European Society of Clinical Oncology). She is also a member of the Board of Director of NIBIT Foundation, of IMI and of Federation of Italian Cooperative Oncology Groups (FICOG). She is member of Steering Committee of ESMO Immuno-oncology.

Dr. Di Giacomo has been the Principal Investigator and Co-Investigator for more than 150 clinical trials in solid malignancies, investigating bio-chemotherapy, immunotherapeutic agents and molecularly targeted agents. Her clinical and translational research interests include: the immunological and clinical activity of immunotherapeutic agents including the new generation of targeted immunotherapy in the treatment of skin, brain and other solid tumours; epigenetics and epigenetic-immuno-sequencing strategies to improve efficacy of cancer immunotherapy; identification of biomarkers of efficacy of cancer immunotherapy.

All manuscripts submitted to this Article Collection will undergo desk assessment and peer-review as part of our standard editorial process. Please review the journal Aims and Scope and author submission instructions prior to submitting a manuscript.

The deadline for submissions is 30th April 2024.

Please submit   your manuscript on our website, quoting the promo code ZDDYW to indicate that your submission is for consideration in this Article Collection.

Please contact Marya Baig at [email protected] with any queries and discount codes regarding this Article Collection.

Instructions for AuthorsSubmit an Article