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Expert Opinion on Investigational Drugs- Investigational drugs to impact metabolic dysfunctions that fuel the spectrum of chronic disease

About the special issue

In contrast to areas generally attacked in pharmaceutical development, a brief overview of health care expenditures shows that most of the health care costs come from inadequate treatment of common chronic diseases that cluster together and are significantly impacted by metabolic function. These conditions include type 2 diabetes, fatty liver disease, cardiovascular disease, and neurodegeneration including dementia.

There are currently no effective approaches to treat these overlapping disease states which until recently have seemed a natural consequence of aging. A new paradigm of drug discovery is suggested by molecular connections between common metabolic diseases.

Guest advisor and Key Opinion leader Dr Jerry Colca (Cirius Therapeutics, USA) has teamed up with Expert Opinion on Investigational Drugs in this special issue that brings together various approaches seeking to impact the metabolic dysfunctions that fuel the spectrum of chronic disease.

This collection will emphasize the discovery and evaluation of investigational drugs and drug combinations that might serve a broader purpose. This special interest volume will include agents that were initially targeted to treat specific inflammatory diseases, including type 2 diabetes, which might produce unexpected advantages for maintaining human health in response to environmental challenges.

There is no limitation on which disease states are targeted by investigational treatments. Topics may include:

• Reducing metabolic inflexibility

• Harnessing the power of immunomodulation

• Reducing neuroinflammation.

The issue welcomes authors to submit relevant editorials, reviews, interviews, and original research. If you are interested in contributing, or would like to learn more, then please reach out to the Commissioning Editor, Ryan Gilroy, who will be happy to assist.

Submission information

Submission Deadlines:

Standard track: 12th August 2024

Rapid track: 2nd September 2024

Fast track: 30th September 2024



Accelerated Publication

Publish in 3 – 5 weeks from submission

Submission to acceptance: 2 – 3 weeks
1 – 2 weeks for peer review
1 week for author revision

Acceptance to online publication: 1 – 2 weeks, with proofs within 5 working days and 48 hours for author review

Cost per article: $7000 / €6200 / £5500

Publish in 7 – 9 weeks from submission

Submission to acceptance: 5 – 6 weeks
3 – 4 weeks for peer review
2 weeks for author revision

Acceptance to online publication: 2 – 3 weeks, with proofs within 10 working days

Cost per article: $3900 / €3400 / £3000


By publishing in Expert Opinion on Investigational Drugs you will:

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  • Receive 50 free e-prints & promotional tips on promoting your article courtesy of our Author Services site

  • Immediately see the impact of your research made in the community by tracking downloads, citations, and the Altmetric Score of your article on My Authored Works

  • Increase the discoverability of your research with MEDLINE listings and more

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