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Virtual Special Issue: Autophagy in host-pathogen interactions


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Autophagy is a key cellular process not only for the recycling of proteins and organelles, but also as the first line of defence against intracellular pathogens. This Virulence Special Issue examines the intricate interplay between the autophagy machinery of animal or plant hosts and their viral, bacterial, fungal and protozoan pathogens. A series of reviews and one research article examine the significance of autophagy for the infection by, and defence against, enteroviruses, influenza, HIV, tuberculosis, Trypanosoma, Toxoplasma and other microorganisms, and present the various ways the autophagic process can be subverted by these pathogens to their own benefit and therapeutically target to the benefit of the host.