Women’s Health & Sex Differences in ADME Research

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About the Article Collection

Women are underrepresented in clinical trials and research often does not look at the differences between how men and women respond to treatments. This, combined with the fact women are more likely to suffer from certain diseases, has led to an inequality in both our understanding of and the consequent medical treatment women receive. 

Research into the absorption, distribution, metabolism and excretion (ADME) of therapeutics is imperative to drug development and drug safety. We must amplify the ADME research that focuses on women to create more inclusive and effective medical practice. 

With contributions from world-class key opinion leaders across academia and industry, this Article Collection will showcase literature focused on ADME research in women’s health. It will also delve into the influences of sex and gender on the metabolic pathways, pharmacokinetics and toxicological outcomes.

The Collection welcomes authors to submit relevant editorials, reviews, perspectives, pharmacokinetic evaluations and original research.  The benefit of publishing as part of an Article Collection is that they often become a key resource, driving a research community forward. This has a synergistic effect on every article in the Collection.

Topics of interest include:

  • Metabolic, pharmacokinetic and toxicological issues relating to drugs specifically for women 

  • Pharmacokinetic evaluations of drugs used primarily by women 

  • Drug interactions in diseases experienced by women; breast cancer, ovarian cancer, polycystic ovaries, endometriosis etc. 

  • Pharmacokinetics of drugs during pregnancy and child birth 

  • Sex and gender differences in metabolic pathways, pharmacokinetics and toxicological outcomes – and a look at the clinical implications of these. Example

We are delighted to be working alongside the guest advisors; Flavia Franconi and Ilaria Campesi

If you are interested in contributing, or would like to learn more, then please reach out to the Commissioning Editor, Amelia Dennis, who will be happy to assist. 

About the Guest Advisors

Professor Flavia Franconi

Flavia Franconi was full time professor of  Pharmacology,  University  of  Sassari  (1986-2017)  where  she founded and directed the PhD course in Gender Pharmacology (2004-2014). She was founder and president of Giseg (Italian Group Salute e medicina di genere) and of the Gender Pharmacology Group of the  Italian  Society  of  Pharmacology in 2003, and member of working group of AIFA “Farmaci e Genere”.

She collaborated with UNICRI and UN for the preparation of the document for the UN resolution of 1 March 2011 (www.un.org/womenwatch/daw/egm/gst_2010/).

She is the Coordinator of the Gender  Medicine  Platform  of  the  Interuniversity  Consortium INBB. From 2021-2024 she was a member of the National Observatory of Gender Medicine and spokesperson for the Gender Pharmacology Working Group. Since 2021 she has been the coordinator of the Equity in Health of WG. She is member of following editorial board: Biology of Sex Differences Frontiers in Cardiovascular Medicine – Sex and Gender in Cardiovascular Medicine.

She has written more than more than 230 papers published in international journals and books and 76 of them are involved in studying sex and gender aspect in medicine and pharmacology. 

Dr Ilaria Campesi

Ilaria Campesi received her PhD in Gender Pharmacology from the University of Sassari, Italy in 2010. Her research focuses primarily on the identification of sex-gender-specific humoral and cellular markers in the cardiovascular field and related diseases (inflammation, diabetes) during prenatal life and in the adulthood. She is the author / co-author of 74 publications in international journals.

Submission Information

Submission Deadlines:

Standard track: September 6th, 2024

Accelerated Publication 7-9 weeks track: October 25th, 2024

Accelerated Publication 3-5 weeks track: November 22nd, 2024

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