Women’s Health & Sex Differences in ADME Research

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Expert Opinion on Drug Metabolism & Toxicology’s Latest Call for Papers

Women are underrepresented in clinical trials and research often does not look at the differences between how men and women respond to treatments. This, combined with the fact women are more likely to suffer from certain diseases, has led to an inequality in both our understanding of and the consequent medical treatment women receive. 

Research into the absorption, distribution, metabolism and excretion (ADME) of therapeutics is imperative to drug development and drug safety. We must amplify the ADME research that focuses on women to create more inclusive and effective medical practice. 

With contributions from world-class key opinion leaders across academia and industry, this article collection will showcase literature focused on ADME research in women’s health. It will also delve into the influences of sex and gender on the metabolic pathways, pharmacokinetics and toxicological outcomes. 

We are delighted to be working alongside the guest advisors; Flavia Franconi and Ilaria Campesi. 

The collection welcomes authors to submit relevant editorials, reviews, perspectives, pharmacokinetic evaluations and original research. The benefit of publishing as part of an article collection is that they often become a key resource, driving a research community forward. This has a synergistic effect on every article in the issue. 

If you are interested in contributing, or would like to learn more, then please reach out to the Commissioning Editor, Amelia Dennis, who will be happy to assist. 

We welcome these submissions:

• Metabolic, pharmacokinetic and toxicological issues relating to drugs specifically for women 

• Pharmacokinetic evaluations of drugs used primarily by women 

• Drug interactions in diseases experienced by women; breast cancer, ovarian cancer, polycystic ovaries, endometriosis etc. 

• Pharmacokinetics of drugs during pregnancy and child birth 

• Sex and gender differences in metabolic pathways, pharmacokinetics, and toxicological outcomes – and a look at the clinical implications of these. 

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