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Emerging and Re-emerging Coronaviruses

Emerging Microbes and Infections

Guest Editor: Dr. Susan R Weiss, Perelman School of Medicine, University of Pennsylvania, USA

Emerging and re-emerging coronaviruses, including Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV), Middle East Respiratory Syndrome Coronavirus (MERS-CoV) and the latest “Wuhan Coronavirus” may cause epidemics or potentially pandemics of highly pathogenic human infectious diseases, posing great threats to the global health.

EMI's Special Issue on Emerging and Re-emerging Coronaviruses covers research and review articles on the basic, translational and clinical studies related to these coronaviruses. As an Open Access journal, all articles in EMI are fully downloadable.

Article Authors
Risk factors associated with COVID-19 infection: a retrospective cohort study based on contacts tracing T. Liu, W. Liang, H. Zhong et al.
Epidemiology and clinical course of COVID-19 in Shanghai, China Y. Shen , F. Zheng , D. Sun et al.
Organising a COVID-19 Triage Unit: a Swiss Perspective G. Peros, F. Gronki, N. Molitor et al.
Serological differentiation between COVID-19 and SARS infections W. N. Chia, C. W. Tan, R. Foo et al.
Kawasaki-like diseases and thrombotic coagulopathy in COVID-19: delayed over-activation of the STING pathway? J. M. Berthelot , L. Drouet & F. Lioté
Retrospective detection of SARS-CoV-2 in hospitalized patients with influenza-like illness X. Yu, D. Wei, Y. Chen et al.
Development of an automatic integrated gene detection system for novel Severe acute respiratory syndrome-related coronavirus (SARS-CoV 2) Y. Li , J. Li , Y. Zhang et al.
Virus strain from a mild COVID-19 patient in Hangzhou represents a new trend in SARS-CoV-2 evolution potentially related to Furin cleavage site X. Jin, K. Xu, P. Jiang et al.
Antibodies in the breast milk of a maternal woman with COVID-19 Y. Dong, X. Chi, H. Hai et al.
SARS-CoV-2 genomic surveillance in Taiwan revealed novel ORF8-deletion mutant and clade associated with infections in Middle East Y. N. Gong, K. C. Tsao, M. J. Hsiao et al.
Epidemiology of COVID-19 in Brazil: using a mathematical model to estimate the outbreak peak and temporal evolution Y. Tang, T. D. A. Serdan, L. N. Masi et al.
SARS-CoV-2 nsp13, nsp14, nsp15 and orf6 function as potent interferon antagonists C. K. Yuen, J. Y. Lam, W. M. Wong et al.
Experimental Aerosol Survival of SARS-CoV-2 in Artificial Saliva and Tissue Culture Media at Medium and High Humidity S. J. Smither, L. S. Eastaugh, J. S. Findlay & M. S. Lever
Targeting SARS-CoV-2 Receptors as a Means for Reducing Infectivity and Improving Antiviral and Immune Response: An Algorithm-based Method For Overcoming Resistance To Antiviral Agents R. Gelman, A. Bayatra, A. Kessler et al.
Laboratory management for SARS-CoV-2 detection: a user-friendly combination of the heat treatment approach and rt-Real-time PCR testing F. Mancini, F. Barbanti, M. Scaturro et al.
The burden, admission, and outcome of COVID-19 in Africa: Protocol for a Systematic Review and Meta-analysis D. B. Tadesse, G. G. Gebremeskel, G. G. Asefa et al.
Nurse Infected with Covid-19 from a Provisional Dengue Patient W. Prasitsirikul, K. Pongpirul, W. A. Pongpirul et al.
COVID-19 pandemic – An African perspective S. A. Lone & A. Ahmad
Evaluating the use of posterior oropharyngeal saliva in a point-of-care assay for the detection of SARS-CoV-2 J. H. K. Chen, C. C. Y. Yip, R. W. S. Poon et al.
Genetic cluster analysis of SARS-CoV-2 and the identification of those responsible for the major outbreaks in various countries X. Yang, N. Dong, E. W. C. Chan & S. Chen
Patterns of IgG and IgM antibody response in COVID-19 patients X. Liu, J. Wang, X. Xu et al.
Dynamic surveillance of SARS-CoV-2 shedding in children with COVID-19 P. Liu, J. Cai. R. Jia et al.
Structural basis of HCoV-19 fusion core and an effective inhibition peptide against virus entry H. Sun, Y. Li, P. Liu et al.
Viral loads in throat and anal swabs in children infected with SARS-CoV-2 C. Yuan, H. Zhu, Y. Yang et al.
Clinical Characteristics of Foreign-Imported COVID-19 Cases in Shanghai, China X. Liu, S. H. Lu, J. Chen et al.
Analytical comparisons of SARS-COV-2 detection by qRT-PCR and ddPCR with multiple primer/probe sets X. Liu, J. Feng, Q. Zhang et al.
Gemcitabine, lycorine and oxysophoridine inhibit novel coronavirus (2019-nCoV) in cell culture Y. N. Zhang, Q. Y. Zhang, X. D. Li et al.
Delayed specific IgM antibody responses observed among COVID-19 patients with severe progression L. Shen, C. Wang, J. Zhao et al.
Profiling serum cytokines in COVID-19 patients reveals IL-6 and IL-10 are disease severity predictors H. Han, Q. Ma, C. Li et al.
Social distancing: how religion, culture and burial ceremony undermine the effort to curb COVID-19 in South Africa I. F. Jaja, M. U. Anyanwu & C. J. I. Jaja
Development of multi-specific humanized llama antibodies blocking SARS-CoV-2/ACE2 interaction with high affinity and avidity J. Dong, B. Huang, Z. Jia et al.
Development of reverse transcription - loop-mediated isothermal amplification as a rapid early-detection method for novel SARS-CoV-2 Y. H. Baek, J. H. Um, K. J. C. Antigua et al.
Isolation of Infectious SARS-CoV-2 from Urine of a COVID-19 Patient J. Sun, A. Zhu, H. Li et al.
Impact of population movement on the spread of 2019-nCoV in China C. Zhang, C. Chen, W. Shen et al.
Animal Models for Emerging Coronavirus: Progress and New Insights L. Yuan, Q. Tang, T. Cheng & N. Xia
Kinetics of SARS-COV-2 specific IgM and IgG antibody responses in COVID-19 patients B. Sun, Y. Feng, X. Mo et al.
Significance of Serology Testing to Assist Timely Diagnosis of SARS-CoV-2 infections: Implication from a Family Cluster Y. Xu, M. Xiao, X. Liu et al.
Lack of cross neutralization by SARS patient sera towards SARS-CoV-2 D. E. Anderson, C. W. Tan, W. N. Chia et al.
Attenuated SARS-CoV-2 variants with deletions at the S1/S2 junction S. Y. Lau, P. Wang, B. W. Y. Mok et al.
Different longitudinal patterns of nucleic acid and serology testing results based on disease severity of COVID-19 patients Y. Zhang, H. Shen, X. Wang et al.
Rheumatologists’ View on the Use of Hydroxychloroquine to Treat COVID-19 X. Sun, Y. Ni & M. Zhang
Mathematic Modeling of COVID-19 in the United States Y. Tang & S. Wang
Diagnostic Value and Key Features of Computed Tomography in Coronavirus Disease 2019 B. Li, X. Li, Y. Wang et al.
Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients Y. Xiong, Y. Liu, L. Cao et al.
Renin-angiotensin system inhibitors improve the clinical outcomes of COVID-19 patients with hypertension J. Meng, G. Xiao, J. Zhang et al.
Hypothesis for potential pathogenesis of SARS-CoV-2 infection——a review of immune changes in patients with viral pneumonia L. Lin, L. Lu, W. Cao & T. Li
Laboratory Diagnosis of Emerging Human Coronavirus Infections — The State of the Art M. J. Loeffelholz & Y. W. Tang
The different clinical characteristics of corona virus disease cases between children and their families in China --the character of children  with COVID-1 L. Su, X. Ma, H. Yu et al.
Clinical Observation and Management of COVID-19 Patients T. Li, H. Lu & W. Zhang
Establishment and validation of a pseudovirus neutralization assay for SARS-CoV-2 J. Nie, Q. Li, J. Wu et al.
Emerging WuHan (2019-nCoV) Coronavirus: Glycan shield and structure prediction of Spike glycoprotein and its interaction with Human  CD26 N. Vankadari & J. A. Wilce
Era of molecular diagnosis for pathogen identification of unexplained pneumonia, lessons to be learned J. W. Ai, Y. Zhang, H. C. Zhang et al.
A tug-of-war between severe acute respiratory syndrome coronavirus 2 and host antiviral defense: Lessons from other pathogenic viruses S. Y. Fung, K. S. Yuen, Z. W. Ye et al.
Diagnosis and clinical management of severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) infection: an operational recommendation of Peking Union Medical College Hospital (V2.0) Taisheng Li
Timely Development of Vaccines against SARS-CoV-2 Shan Lu
Is SARS-CoV-2 originated from laboratory? A rebuttal to the claim of formation via laboratory recombination P. Hao, W. Zhong, S. Song et al.
Systematic, active surveillance for Middle East respiratory syndrome coronavirus in camels in Egypt M. A Ali, M. M Shehata, M. R Gomaa et al.
Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody X. Tian, C. Li, A. Huang et al.
Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes W. Zhang, R. H. Du, B. Li et al.
HIV-1 did not contribute to the 2019-nCoV genome C. Xiao, X. Li, S. Liu et al.
RNA based mNGS approach identifies a novel human coronavirus from two individual pneumonia cases in 2019 Wuhan outbreak L. Chen, W. Liu, Q. Zhang et al.
An emerging coronavirus causing pneumonia outbreak in Wuhan, China: calling for developing therapeutic and prophylactic strategies S. Jiang, L. Du & Z. Shi
Discovery of a subgenotype of human coronavirus NL63 associated with severe lower respiratory tract infection in China, 2018 Y.Wang, X. Li, W. Liu et al.
Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan J. F. W. Chan, K. H. Kok, Z. Zhu et al.
Polymorphisms in dipeptidyl peptidase 4 reduce host cell entry of Middle East respiratory syndrome coronavirus H. Kleine-Weber, S. Schroeder, N. Krüger et al.
Genetic manipulation of porcine deltacoronavirus reveals insights into NS6 and NS7 functions: a novel strategy for vaccine design M. Zhang, W. Li, P. Zhou et al.
Serological evidence of MERS-CoV and HKU8-related CoV co-infection in Kenyan camels W. Zhang, X. S. Zheng, B. Agwanda et al.
GILT restricts the cellular entry mediated by the envelope glycoproteins of SARS-CoV, Ebola virus and Lassa fever virus D. Chen, Z. Hou, D. Jiang et al.
Antibodies and vaccines against Middle East respiratory syndrome coronavirus J. Xu, W. Jia, P. Wang et al.
Towards a solution to MERS: protective human monoclonal antibodies targeting different domains and functions of the MERS-coronavirus spike glycoprotein I. Widjaja, C. Wang, R. van Haperen et al.
Genetic relatedness of the novel human group C betacoronavirus to Tylonycteris bat coronavirus HKU4 and Pipistrellus bat coronavirus HKU5 P. C. Y Woo, S. K. P. Lau, K. S. M. Li et al.
Middle East respiratory syndrome coronavirus M protein suppresses type I interferon expression through the inhibition of TBK1-dependent phosphorylation of IRF3 P. Y. Lui, L. Y. R. Wong, C. L. Fung et al.
Understanding the T cell immune response in SARS coronavirus infection H. L. J. Oh, S. K. E. Gan, A. Bertoletti & Y. J. Tan
A camel-derived MERS-CoV with a variant spike protein cleavage site and distinct fusion activation properties J. K. Millet, M. E. Goldstein, R. N. Labitt et al.
Polyphyletic origin of MERS coronaviruses and isolation of a novel clade A strain from dromedary camels in the United Arab Emirates S. K. P. Lau, R. Wernery, E. Y. M. Wong et al.
Identification and evolutionary dynamics of two novel human coronavirus OC43 genotypes associated with acute respiratory infections: phylogenetic, spatiotemporal and transmission network analyses X. Y. Oong, K. T. Ng, Y. Takebe et al.
Coronavirus HKU15 in respiratory tract of pigs and first discovery of coronavirus quasispecies in 5′-untranslated region P. C. Y. Woo, S. K. P. Lau, C. C. Tsang et al.
Diversity and role of cave-dwelling hematophagous insects in pathogen transmission in the Afrotropical region J. Obame-Nkoghe, E. M. Leroy & C. Paupy
Longitudinal study of Middle East Respiratory Syndrome coronavirus infection in dromedary camel herds in Saudi Arabia, 2014–2015 M. G. Hemida, A. Alnaeem, D. K. W. Chu et al.
Diversity of Middle East respiratory syndrome coronaviruses in 109 dromedary camels based on full-genome sequencing, Abu Dhabi, United Arab Emirates M. F. Yusof, K. Queen, Y. M. Eltahir et al.
Discovery and genetic analysis of novel coronaviruses in least horseshoe bats in southwestern China L. Wang, S. Fu, Y. Cao et al.
Replication of MERS and SARS coronaviruses in bat cells offers insights to their ancestral origins S. K. P. Lau, R. Y. Y. Fan, H. K. H. Luk et al.
A novel human coronavirus OC43 genotype detected in mainland China Y. Zhu, C. Li, L. Chen et al.
Genomic characterization and infectivity of a novel SARS-like coronavirus in Chinese bats D. Hu, C. Zhu, L. Ai et al.
Human coronavirus OC43 outbreak in wild chimpanzees, Côte d´Ivoire, 2016 L. V. Patrono, L. Samuni, V. M. Corman et al.
The emergence of novel sparrow deltacoronaviruses in the United States more closely related to porcine deltacoronaviruses than sparrow deltacoronavirus HKU17 Q. Chen, L. Wang, C. Yang et al.

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