Stress is a major public health issue affecting millions of people worldwide and can lead to a range of mental and physical health problems, including anxiety, depression, and PTSD. A better understanding of the underlying molecular mechanisms of stress and stress-related disorders is essential for developing more effective treatments and interventions. Multi-omics approaches have emerged as powerful tools for studying the complex interplay between genes, the environment, and stress, providing a comprehensive understanding of the cellular and molecular mechanisms of stress. By utilizing these tools, we can generate new hypotheses that will drive the field forward.
The proposed article collection, “Beyond the Surface: Multi-Omics Insights into Stress and its Effects”, aims to gather the latest research on multi-omics approaches to stress and stress-related disorders. The collection will focus on identifying cellular, molecular, genetic, and microbiomic biomarkers associated with stress susceptibility, characterizing the molecular pathways underlying stress responses and predicting druggable targets against stress. By bringing together this research, we hope to advance our understanding of the underlying cellular and molecular mechanisms of stress with particular emphasis on new hypothesis-generating studies that utilize these multi-omics approaches.
Original research articles on this critical topic are welcome. Submissions should focus on multi-omics approaches to stress and stress-related disorders, emphasizing the omics subfields of genomics, transcriptomics (bulk and single cell), proteomics, metabolomics, epigenomics, kinomics, and microbiomics. Possible subtopics of interest include genetic and environmental factors in stress susceptibility, the role of epigenetics in stress responses, and the identification of druggable targets and biomarkers associated with stress-related disorders.
