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Renal Failure

For an Article Collection on

Applying Complex Technologies in ICU: CRRT Use with LVAD and ECMO

Manuscript deadline
29 February 2024

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Article collection guest advisor(s)

Prof. Guangtao Xu, Department of Pathology, Jiaxing University, China

Prof. Jian Hou, The First Affiliated Hospital of Sun Yat-sen University, China

Prof. Zhongkai Wu, The First Affiliated Hospital of Sun Yat-sen University, China

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Applying Complex Technologies in ICU: CRRT Use with LVAD and ECMO

Extracorporeal membrane oxygenation (ECMO) and left ventricular assist device (LVAD) are proven to be life-saving therapies for patients with severe cardiopulmonary failure. As the indicators for these therapies continue to expand, their use in critically ill patients and in the Intensive Care Unit (ICU) is on the rise. Patients who require ECMO and LVAD have substantial hemodynamic, inflammatory, and pathophysiologic abnormalities that put them at high risk for other organ failures, particularly renal failure. This underscores the need for continuous renal replacement therapy (CRRT) treatment.

However, for patients who require both CRRT and ECMO/LVAD, there is significant variation in practice regarding the use of renal support therapy during ECMO/LVAD. This remains an important question to explore how to adapt the optimal regimen to the patient’s reality in order to seek the best prognosis.

This article collection aims to provide insights into the indications, timing, implementation, and prognosis for critically ill renal disease or kidney injury (primary or secondary renal lesions) patients requiring combined use of CRRT and ECMO/LVAD.

Any article types consistent with Renal Failure's author guidelines that investigate the following aspects are welcomed:

1) Analysis of risk factors in patients with CRRT use with LVAD and/or ECMO in ICU.

2) Opportunities for incremental improvement of conventional multidisciplinary treatments in primary or secondary renal lesions.

3) Predictive analytics and early intervention for ICU patients with or at risk for renal dysfunctions.

4) Application of blood purification techniques in envenomated patients with or at risk for renal dysfunctions.

5) Renal support for the critical care: Innovations in CRRT, LVAD, and ECMO therapies.

Keywords: CRRT, ECMO, LVAD, ICU


Guest Advisors

Prof. Guangtao Xu, M.D. is an Associate Editor of Renal Failure and Academic Editors of several journals. He is an Associate Professor and Director at the Department of Pathology at the Jiaxing University, Jiaxing, ZJ, China. His team's research focuses on renal ischemia reperfusion injury.

Prof. Jian Hou, Ph.D. is an Associate Researcher at the Department of Cardiac Surgery of 1st Affiliated Hospital of Sun Yat-sen University, Guangzhou, GD, China. Her research focuses on cardio-renal preservation.

Prof. Zhongkai Wu, M.D., Ph.D. is a Professor and Director of the Department of Cardiac Surgery, 1st Affiliated Hospital of Sun Yat-sen University and a Co-director of the Key Lab of Assisted Circulation, Ministry of Health of China. He has long been engaged in research on multiple organ protection in cardiac surgery.

Disclosure statement: Guest Advisors declare there is no conflict of interest.


All manuscripts submitted to this Article Collection will undergo a full peer-review; the Guest Advisor for this Collection will not be handling the manuscripts (unless they are an Editorial Board member).

Please review the journal scope and author submission instructions prior to submitting a manuscript.

The deadline for submitting manuscripts is February 29th, 2024.

Please contact Ruby Ru at [email protected] with any queries and discount codes regarding this Article Collection.

To submit your papers to this Article Collection, please:

  1. Check "yes" for the question, "Are you submitting your paper for a specific special issue or article collection?"
  2. Select the relevant Article Collection from the drop-down menu under the question, "Special Issue or Article Collection Name."

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All manuscripts submitted to this Article Collection will undergo desk assessment and peer-review as part of our standard editorial process. Guest Advisors for this collection will not be involved in peer-reviewing manuscripts unless they are an existing member of the Editorial Board. Please review the journal Aims and Scope and author submission instructions prior to submitting a manuscript.