Journal of Taibah University for Science

Advanced Nanoengineered Hybrid Biosensors for Biomedical and Pharmaceutical Analysis

Journal of Taibah University for Science is pleased to welcome you to submit your research to the Article Collection "Advanced Nanoengineered Hybrid Biosensors for Biomedical and Pharmaceutical Analysis".

Modern healthcare and pharmaceutical industries are currently facing unprecedented challenges due to the rapid increase in chronic diseases, emerging infectious pathogens, antimicrobial resistance, environmental pollution, and the growing need for personalized medicine. Diseases such as cancer, diabetes, cardiovascular disorders, neurological diseases, and viral infections require early diagnosis and continuous monitoring to improve patient outcomes and reduce mortality rates. At the same time, pharmaceutical analysis demands highly accurate, rapid, and cost-effective analytical tools for drug discovery, therapeutic monitoring, quality control, and real-time assessment of bioactive compounds. Conventional analytical and diagnostic techniques, although highly reliable, often suffer from limitations such as expensive instrumentation, time-consuming procedures, complex sample preparation, lack of portability, and the requirement for skilled personnel. These limitations have created a significant demand for next-generation biosensing platforms capable of delivering rapid, ultrasensitive, selective, and point-of-care detection. In recent years, biosensor technology has emerged as a transformative solution for addressing these healthcare and pharmaceutical challenges. Biosensors offer the advantages of real-time analysis, miniaturization, portability, low sample consumption, and high analytical performance. However, the increasing complexity of biological systems and the need for ultra-low detection limits have accelerated the development of advanced nanoengineered hybrid biosensors. The integration of nanotechnology with biosensing systems has significantly improved sensitivity, conductivity, biocompatibility, catalytic activity, and signal amplification.

Hybrid nano biosensor engineering has gained immense importance because it combines the exceptional physicochemical properties of multiple nanomaterials with the selectivity of biological recognition systems, enabling the development of highly efficient and multifunctional sensing platforms. Unlike conventional biosensors, hybrid nano biosensors integrate materials such as metal nanoparticles, graphene, carbon nanotubes, quantum dots, MXenes, conducting polymers, and metal oxides to achieve synergistic improvements in sensitivity, selectivity, biocompatibility, electron transfer, and signal amplification. These unique features allow rapid and ultrasensitive detection of disease biomarkers, pathogens, pharmaceutical compounds, and toxic substances even at extremely low concentrations. Their transformative applications in biomedical and pharmaceutical sciences are particularly significant for early disease diagnosis, personalized medicine, therapeutic drug monitoring, wearable healthcare devices, and point-of-care testing. Furthermore, hybrid nano biosensors support real-time analysis, portability, low-cost operation, and miniaturization, making them highly suitable for decentralized healthcare and resource-limited settings. In this context, advanced nanoengineered hybrid biosensors represent a highly promising interdisciplinary research area that bridges materials science, nanotechnology, electrochemistry, biotechnology, and biomedical engineering.

This article collection aims to highlight recent advances, innovative designs, emerging materials, and practical applications of nanoengineered hybrid biosensors for biomedical and pharmaceutical analysis, while addressing current challenges and future opportunities for next-generation sensing technologies. Original research articles and short communications related to electrochemical, optical, fluorescence, photoelectrochemical, wearable, flexible, and point-of-care biosensors are welcome. Topics of interest include, but are not limited to:

• Nanoengineered hybrid biosensing materials
• Electrochemical and optical biosensors
• Carbon nanomaterial-based biosensors
• Quantum dot and MXene hybrid sensing platforms
• Conducting polymer nanocomposite biosensors
• Thin-film and flexible biosensors
• Plasmonic and photoelectrochemical biosensors
• Wearable and implantable biosensors
• Point-of-care diagnostic devices
• Nanozyme-assisted sensing technologies
• AI-integrated intelligent biosensors
• Surface engineering and signal amplification
• Biosensors for pharmaceutical analysis
• Detection of drugs and therapeutic agents
• Cancer biomarker sensing
• Glucose, dopamine, uric acid, and neurotransmitter sensors
• Aptasensors and immunosensors
• Green synthesis and sustainable nanomaterials
• Microfluidic and lab-on-chip biosensors

Meet the Guest Advisors

Dr. JG Manjunatha is working as an Associate Professor in Chemistry at FMKMC College, A Constituent College of Mangalore University, Madikeri, India. He received his Ph.D. degree in Chemistry from Kuvempu University and a postdoc from the University of Kebangsaan Malaysia. He has received various awards and published more than 245 research articles in reputed International Journals. An editor for 35 books (RSC, Springer, Willy, ACS, IOP, Elsevier, and Bentham Science Publishers), and special issues (IOP Science Publisher, Frontiers in Sensors, MDPI). He is also an editorial board member for many reputed journals and Editor-in-Chief of the Sensing Technology journal (Taylor & Francis).

Dr. Thiago C Canevari received his PhD in Materials Chemistry from the State University of Campinas, Brazil, in 2012, and his postdoctoral internship in nanotechnology from the University of São Paulo (USP-São Paulo) in 2017. He is a scholarship holder for Productivity in Technological Development and Innovative Extension - DT 2 from CNPq and a professor and researcher of the postgraduate program in Materials Engineering and Nanotechnology. His research interests include Multifunctional hybrid nanomaterials, nanotechnology, and (Bio) electrochemical sensors. He has authored/co-authored about 41 articles published in international journals.

The Guest Advisors declare no conflict of interest regarding this work.