International Journal of Nanomedicine

Surfactants, classified as amphiphilic compounds, have evolved significantly in response to recent technological advancements. These innovations enable precise tuning of their charge, chain length, and physicochemical properties to meet specific needs. These versatile compounds play a pivotal role in a wide array of applications, spanning from adhesives, paints, cosmetics, household and industrial cleaners, oilfield chemicals, pesticides, plastics, textiles, food, and pharmaceuticals. They are indispensable for promoting a healthy and comfortable human lifestyle.

Notably, there is a growing utilization of surfactants in the burgeoning field of nanomedicine, driven by strides in nanotechnology. Prominent examples include their role as templates for crafting nanoparticles, as key components in niosomes, and as solubilizers for proteins and antibodies. Furthermore, surfactants hold the potential to impart advanced functionalities in nanomedicine, including the ability to regulate capture by the mononuclear phagocyte system (MPS) within the body, mitigate hemolysis, target specific organs, and mitigate adverse drug effects.

The potential of surfactants in nanomedicine is expansive, and research results have demonstrated significant promise in various medical domains. These include oncology, cardiovascular diseases, neurodegenerative diseases, gastroenterological diseases, dermatological conditions, ocular disorders, and immunotherapy. Particularly noteworthy are the achievements observed when utilizing surfactants series of poloxamer and polysorbate. In essence, surfactants, with their enduring historical legacy spanning ancient civilizations to the modern era, remain indispensable to human existence. They continue to adapt and find relevance in emerging fields of application.

The primary objective of this collection of articles is to spotlight the forefront of nanomedicine research harnessing the potential of surfactants. This endeavor takes place against the backdrop of an escalating demand for these compounds. Given the wide-reaching versatility of surfactants across a spectrum of research domains, this collection aspires to function as a conduit. It aims to attract not only specialists in nanomedicine but also thought leaders from related disciplines. Through this interdisciplinary exchange, we anticipate the initiation of innovative avenues of scientific exploration.

This article collection comprehensively explores various facets of nanomedicine research leveraging surfactants.

The potential applications encompass a wide spectrum and include, but are not restricted to, the following areas:

• Impact of Surfactants on the Biocompatibility of Nanomedicine
• Enhancing Nanomedicine's Ability to Evade the Mononuclear Phagocyte System (MPS)
• Augmenting Nanomedicine's Targeting Precision
• Preserving the Physical and Chemical Stability of Nanomedicine
• Functional Evaluation of Niosomes Utilizing Surfactants as Building Blocks
• Influence of Surfactants on the Antimicrobial Activity of Nanomedicine
• Modulation of Drug Release Rate by Surfactants in Nanomedicine
• Enhancing Nanomedicine's Dispersibility
• Surfactant-Mediated Enhancement of Therapeutic Efficacy
• Future Directions and Challenges in the field of nanomedicine utilizing surfactants

This comprehensive coverage underscores the pivotal role surfactants play in advancing nanomedicine research across a multitude of dimensions, offering a promising avenue for innovations in healthcare and therapeutic interventions.

All manuscripts submitted to this Article Collection will undergo full peer-review; Guest Advisors will not be handling submitted articles. Please review the journal’s aims and scope and author submission instructions prior to submission.

Please submit your manuscript through the Dovepress website. During submission, enter the promo code JWYJL to indicate that your article should be considered for this Collection.

Please contact Haoyang Yi at [email protected] with any queries regarding this Article Collection.

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Guest Advisors:

Dr. Taiki Miyazawa, Tohoku university

Taiki Miyazawa has been an associate professor at the Tohoku university, New industry creation hatchery center (Niche). He received Ph.D. from Tohoku university in April 2014. His research focuses on carotenoids, polyphenols, and vitamins with the aim of elucidating the biological activities of these components. He is also working on the application of nanoparticle-based nanomedicine to efficiently utilize these food components and other pharmaceuticals in the body. He also been developing an AI system for explain the physiological functions exhibited by thousands of molecular species in foods.

Dr. Maharshi Bhaswant, Tohoku university

Maharshi Bhaswant is currently a JSPS research fellow at Tohoku University, based at the New Industry Creation Hatchery Center (Niche). He completed his Ph.D. degree at Victoria University in Melbourne, Australia, in the year 2016. His primary research focus revolves around natural molecules, with the overarching goal of gaining a comprehensive understanding of their cardiometabolic properties and functions. Furthermore, his research extends to the practical application of micronutrients, with the aim of effectively fortifying these vital components within various food constituents, thereby contributing to improved health and overall well-being. Maharshi's research interests also encompass the identification and assessment of novel therapeutic molecules for the treatment of chronic diseases.

Dr. Hiroaki Komuro, Cedars-Sinai Medical Center

Hiroaki Komuro has been a postdoctoral fellow at the Smidt Heart Institute, Cedars-Sinai Medical Center, US. In march 2021, he received a Ph.D under the guidance of professor Tetsuo Sasano at Department of Cardiovascular Medicine, Tokyo Medical and Dental University in Japan. His research interests include development of therapeutic and diagnostic using biomaterials, especially extracellular vesicles.

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