Gut Microbes Reports

The blood microbiome has become something of a controversial topic over the last several years, with opinions divided over whether a stable, low biomass blood microbiome exists or whether the microorganisms and their components captured using emerging sequencing technologies reflect a transient, aberrant community that is atypical in healthy individuals. Moreover, research from cases of hematological malignancies have revealed the detrimental impact of high-frequency, antimicrobial exposures on the intestinal microbiome, and the resulting increase in intestinal permeability and bloodstream infections resulting from this reservoir.

In this collection, we seek to compile rigorous studies from multiple geographic regions and covering multiple conditions, in addition to hematologic malignancies. Care should be taken that appropriate negative controls are handled to ensure the validity of data. We seek evidence supporting either side of the blood microbiome debate, but especially those studies that include healthy controls.

Topics may include (but are not limited to):

• Studies of microbial translocation, investing the origin of microorganisms in the blood
• Assessment of the blood microbiome in healthy individuals
• Novel methods/techniques to handle low biomass (blood) samples
• Therapies to reduce/mitigate microbial translocation to the blood
• Temporal/longitudinal studies of the blood microbiome

Instructions for Authors

The following Article Types will be considered: Research Articles, Review Articles, Systematic Reviews, Case Reports, Rapid Communications, Methods, Data Notes, Registered Reports, and Comments.

When submitting your article, please select the Article Collection, ‘Blood Microbiome’ from the drop-down menu on the submission system.

Instructions for AuthorsSubmit an Article