Dove Medical Press is pleased to invite you to submit your research to an upcoming Article Collection on "Beyond Brain Boundaries: Overcoming the Blood-Brain Barrier to Reach the Central Nervous System" in Drug Design, Development and Therapy.
The central nervous system (CNS) is the final frontier in drug delivery due to its intricate network of neurons and complex functions. Despite the increasing prevalence of CNS disorders worldwide, developing effective treatments remains challenging due to exorbitant costs, prolonged clinical pathways, and discouraging failure rates. The formidable barriers guarding the CNS, such as the blood-brain barrier and the blood-cerebrospinal fluid barrier, pose significant challenges, impeding the access of most drugs to their intended targets.
This Article Collection delves into the realm of drug design and explores innovative strategies and breakthrough materials designed to surmount these barriers, facilitating precise and controlled drug delivery to the CNS. The collection aims to unravel the enigma of the CNS by paving the way for transformative therapies that can revolutionize the treatment of neurological and neuropsychiatric disorders.
In addition to exploring innovative strategies and breakthrough materials for drug delivery to the CNS, this article collection also aims to investigate the interplay between neural substrates and non-invasive stimulation techniques. By understanding how different neural substrates interact and respond to non-invasive stimulation (i.e., transcranial magnetic stimulation), researchers aim to develop more targeted and effective therapeutic interventions. This interdisciplinary approach holds the potential to reinvent and rethink the treatment of neurological and neuropsychiatric disorders, offering new possibilities for improved patient outcomes.
Join us as we embark on a journey to uncover the secrets of the central nervous system and pave the way for transformative therapies that can bring about a paradigm shift in the management of neurological and neuropsychiatric conditions. We cordially invite authors to contribute original research and comprehensive review articles.
Please submit your manuscript on our website, quoting the promo code ZDTPN to indicate that your submission is for consideration in this Article Collection.
Guest Advisor Dr. Tanaka's scientific interests include depression, anxiety, dementia, pain, and their comorbidities nature, and translational research in neurological diseases and psychiatric disorders. He is ranked in D1 in Biological Sciences (98%) among Hungarian researchers. His articles have been ranked in the top 99.9 percentile in various fields. He is an editorial board member of Frontiers in Neuroscience, Frontiers in Psychiatry, Anesthesia Research, the Journal of Integrative Neuroscience, Advances in Clinical and Experimental Medicine, and Biomedicines.
Guest Advisor Dr. Battaglia's research experience focuses on the functional interplay of different brain areas involved in emotional learning, action control, brain plasticity, decision-making, and a variety of cognitive tasks. To achieve this aim, his research activity mainly includes the use of non-invasive brain stimulation (i.e., TMS and tDCS), and the recording of different physiological measures using different neuroscientific techniques such as EEG, SCR, HRV, and EMG. He has conducted his research in both healthy individuals, studying intra- and inter-individual differences, and in patients with acquired brain injury. His approach integrates various techniques such as behavioral analysis, electrophysiology, and neurostimulation, aiming to develop groundbreaking therapeutic protocols through cortico-cortical paired associative stimulation (ccPAS). He is an active Editor of several peer-reviewed journals with impact factors.
Guest Advisor Dr. Di Gregorio's scientific interests include psychophysiological correlates of consciousness and disorders of consciousness after severe acquired brain injury. Additionally, his work focused on how cognitive processes are implemented in the human brain, and on translational research in neurological diseases. He is an editorial board member of Advances in Clinical and Experimental Medicine.
Disclosure Statement: Guest Advisors Dr. Tanaka, Dr. Battaglia and Dr. Di Gregorio declare no conflict of interest regarding this work.
