Nanotechnology, Science and Applications

Current Advances in Nanotechnology: Prospects and Challenges of Nanotherapeutics in Treating Cancers

Cancer is a major health issue globally, with an estimated 20 million new cases and 9.7 million deaths in 2022. By 2050, projections indicate a significant increase to over 35 million new cases. Discovering novel medicines is an urgent need. Nanomedicine has emerged as a new multidisciplinary field capturing the attention of scientists. Nanotherapeutics have capabilities for effectively transporting medicines or gene fragments to tumor tissues via passive or active targeting processes; thus there are immense possibilities for enhancing treatment outcomes while causing minimum harm to healthy tissues. Nanoparticles can also be employed for advanced imaging techniques, such as MRI and PET scans, providing better visualization of internal organs and tissues. The engineered nanoparticles can be employed as contrast agents in cancer diagnostics to enable high sensitivity and high-resolution imaging examinations and tumor detection. Novel approaches for tumor labeling and detection are also made possible by the use of nanoprobes. While nanotechnology shows great potential, clinical translation faces challenges related to biocompatibility, toxicity, and the complexity of the tumor microenvironment.

Nanotechnology holds great potential where it enables targeted drug delivery, development of nano-biosensors for early disease detection, and advanced imaging techniques such as MRI and PET scans. Nanoparticles can be designed for improved cancer detection, and enhanced immune responses. Nanoparticles can be employed in the context of radiation sensitization and photothermal therapy to enhance the therapeutic efficacy of malignant tumors. The combination of nanotechnology and conventional tumor therapy can not only enhance the properties of chemoradiotherapy drugs but also reduce the incidence of poisoning and other side effects. These NPs can rapidly cross the human biological barriers, even in a targeted manner and continuously release the content to maintain the appropriate blood concentration of the drug.

Potential subtopics related to recurrent miscarriage include (but are not limited to):

• Bio/molecular nanosystems, nanoparticles including nanoscale bio/therapeutics and nano drug carriers, extracellular vesicles, smart and stimuli responsive nanobiosystems
• Nanotoxicity, nanotoxicology, biomedical sensors including sensor fusion
• Nanomedicine
• Gene therapy
• Biomimetic nanoengineering
• Single particle and single cell analysis, biomedical imaging, nanobiotechnology
• Photothermal therapy
• Nanomedicines in Skin cancer
• Nanomedicines in Lung cancer

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Guest Advisor

Prof. Veena Agrawal, University of Delhi

[email protected]

Professor Veena Agrawal, Senior Professor (R)of Botany (Level-15), University of Delhi, specializes in medicinal plant biotechnology, nanobiotechnology (green synthesis of nanoparticles and their efficacy against, different cancer cells, malaria vectors and diabetes), isolation and characterization of natural biomolecules, sex-linked molecular markers and genetic diversity analysis. She has published over 125 research articles in leading international journals with high impact factors, including Artificial Cells, Nanomedicines, Material Science and Engineering, Industrial Crops, Plant cell reports, Current Cancer Drug Target, Plant Science, Plant Physiology and Biochemistry, Process safety & Environmental Research, etc., Twenty five Ph. D and 21 M.phil. students obtained their degrees under her supervision in different disciplines. She is a Fellow of the Linnean Society of London (FLS) and a member of many international and national academic societies. She is on the editorial board of many journals including Arti. Cells Nanomedicines and Biotechnology. She is on the expert panels of international/national institutions for reviewing and evaluating research projects and Ph,D. theses. She has immensely contributed research to international and national platforms through presentations at conferences, seminars, and publications, as well as registering patents and receiving many awards and recognitions.

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