Annals of Medicine

Diabetes is an ongoing problem and a metabolic pandemic with apparently no country saved. There are several therapeutic actions against it and preventive measures may represent a good and efficient line of attack. Artificial sweeteners have been used for a long time since their inception on the market and on our table. Non-diabetic patients also often use these sweeteners to keep the glucose level under control. Nevertheless, several investigations on experimental animals using cancer bioassays and clinical investigations have raised some concerns on the safe nature of such compounds.

Most recently, the International Association for the Research on Cancer, an agency of the World Health Organization, has emphasized a potential link between aspartame and cancer. There are, obviously, mechanistic data, which seem to be deficient and biases in clinical studies may not be completely removed. The Food and Drug Administration of the United States as well as other food safety agencies in other countries provides a daily intake of artificial sweeteners. Such intake is easily to be reached by both diabetic and non-diabetic individuals raising serious health concerns. In a nutshell, the situation is complex and further investigations are needed.

The subject of this article collection involves the recruitment of clinical studies, cancer bioassays, investigation aimed to mechanistic data, as well as bioinformatics to target this highly relevant and challenging issue that we all face. Narrative, scoping, and systematic reviews are also welcome. Subtopics include all artificial sweetener and their implication to health.

Annals of Medicine accepts the following types of articles:

• Research Articles
• Review Articles
• Clinical Trials
• Protocols
• Case Series
• Commentaries

When submitting your article, please select the section, ‘Oncology’, and the Article Collection, ‘Revealing the Association of Sweeteners with Cancer’ from the drop-down menu on the submission system.

Please contact Sam Zhang at [email protected] with any queries and discount codes regarding this Article Collection.

Annals of Medicine is an online, open access, international journal publishing across all areas of medicine and is part of our Elevate Series. This means that you will receive a concierge-level publishing experience, including dedicated support from our expert in-house Editorial team, with guaranteed response times of within 48 hours, an initial decision on whether your article will be peer reviewed within 5 working days, and a first decision on your research within an average of 22 working days.

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