Nanotechnology, Science and Applications

Uniting Natural Products and Biotechnology for the Next Generation of Nanomedicine

This Article Collection focuses on the convergence of nanotechnology, natural bioactive compounds, and biotechnology to develop advanced therapeutic approaches for a wide range of diseases. The integration of plant-derived phytochemicals, animal-based molecules, and recombinant proteins into nanoscale delivery systems opens new frontiers in precision medicine, offering improved biocompatibility, targeted delivery, and enhanced therapeutic efficacy. Recent advancements in biotechnology have enabled the design and production of engineered proteins and biomolecules with high specificity and functional versatility, further enriching the potential of nanomedical platforms. When combined with the diverse pharmacological properties of naturally sourced compounds, these hybrid nanosystems present promising strategies for treating cancer, infectious diseases, inflammatory conditions, metabolic disorders, and neurodegenerative diseases. This Collection invites original research, reviews, and perspectives that explore the design, synthesis, characterization, and biomedical application of nature-inspired and bioengineered nanostructures. The aim is to provide a multidisciplinary outlook on how the fusion of nanotechnology with natural and recombinant therapeutic agents can drive innovation in diagnosis, treatment, and regenerative medicine.

This Article Collection title encapsulates a timely and significant convergence of nanotechnology, biotechnology, and nature-derived bioactive compounds originating from plant and animal sources. In the context of escalating global health challenges—such as cancer, antimicrobial resistance, chronic inflammation, and neurodegenerative disorders—there is a pressing demand for the development of therapeutic strategies that are not only safe and effective, but also precisely targeted.

Natural molecules exhibit potent biological activity and favorable biocompatibility; however, their clinical potential is often limited by low stability and bioavailability. Advances in biotechnology and nanocarrier systems offer powerful tools to overcome these limitations by enhancing molecular stability, enabling controlled delivery, and improving therapeutic precision. The incorporation of recombinant proteins further broadens the therapeutic arsenal, supporting the design of personalized and multifunctional treatment modalities.

This title reflects the essence of an interdisciplinary approach that synergistically integrates nature’s pharmacological potential with the precision and adaptability of modern scientific innovation. It signals the emergence of a new era in nanomedicine—one in which nanoscale and molecular-level technologies converge to yield next-generation solutions for complex and treatment-resistant diseases.

Please review the journal Aims and Scope and author submission instructions prior to submitting a manuscript. The deadline for submitting manuscripts is 30 June 2026.

Please submit your manuscript on our website, using the promo code F4163 to indicate that your manuscript will be considered for this Article Collection.

Please contact Haoyang Yi (Commissioning Editor) at [email protected] with any queries regarding this Article Collection.

Guest Advisors

Dr. Przemysław Sitarek, Medical University of Lodz

[email protected]

Przemysław Sitarek is an Associate Professor at the Medical University of Łódź (Poland), where he heads the Department of Medical Biology at the Faculty of Pharmacy. His interdisciplinary research spans biotechnology and nanotechnology, with a strong focus on biologically active compounds, recombinant proteins, and metabolic engineering. He is particularly interested in investigating metabolic pathways and developing nature-inspired biomedical solutions to address contemporary therapeutic challenges. His work contributes to advancing the role of both natural and engineered molecules in next-generation nanomedicine.

Dr. Tomasz Kowalczyk, University of Lodz

[email protected]

Tomasz Kowalczyk, PhD, is an assistant professor in the Department of Molecular Biotechnology and Genetics, Faculty of Biology and Environmental Protection, University of Łódź and Department of Medical Biology, Faculty of Pharmacy, Medical University of Lodz. Research interests: Biotechnological production of natural biologically active compounds from plant and other natural sources Development of plant-based and microbial expression systems for production of valuable secondary metabolites and recombinant proteins Application of nanotechnology in combination with biotechnology.

View all papers in this article collection